Barcelona extended their LaLiga lead to eight points thanks to second-half goals by Jordi Alba, Gavi and Raphinha that gave them a 3-0 home win against Sevilla
Barcelona striker Samuel Eto'o finished with 26 goals as he scored in his side's 3-1 defeat at Athletic Bilbao.
Real Madrid tightened their grip on top spot by beating Alaves 3-0 at home in La Liga on Sunday to provisionally move five points ahead of nearest challengers Barcelona despite coach Zinedine Zidane making a string of changes in defence.
Karim Benzema struck twice as Real Madrid went to the top of La Liga with a 4-2 win over Villarreal on Saturday while midfielder Verza's double gave Almeria a shock 2-0 victory over Atletico Madrid.
La Liga leaders Real Madrid dropped points at home for only the second time this season.
In other matches, super-sub Messi helped Barca romp past Atletico
Barca dominated possession and Luis Suarez had several early chances but it was Villarreal who took the lead with Denis Cheryshev redirecting a Mario Gaspar shot past keeper Claudio Bravo on the half hour.
Barcelona's advantage over Real Madrid at the top of La Liga was cut to five points when they surrendered the lead and were held to a 1-1 draw in a thrilling clash at battling Sevilla on Sunday.
News of all that's transpired on and off the football field.
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Real Madrid have reluctantly agreed to play their La Liga match at Rayo Vallecano at 1745 GMT on Monday, a day after the game was abandoned because of alleged lighting sabotage at Rayo's Estadio de Vallecas stadium.
Rampant unbeaten leaders Barcelona ended the first half of the La Liga season with a record 55 of a possible 57 points when Lionel Messi scored one goal and had a hand in two more in a 3-1 win at Malaga on Sunday.
Beat Real Madrid's unbeaten run in the 1988-89 season, and thump Rayo Vallecano 5-1
Atletico Madrid kept pace with leaders Barcelona and restored their five-point lead over third-placed city rivals Real when Diego Costa and David Villa each scored a penalty in a 2-1 win at Granada in La Liga on Thursday.
"We are really pleased and we just have to enjoy it," Celta defender Gustavo Cabral told Spanish television.
Barcelona forward Lionel Messi set a La Liga record of 253 goals when he grabbed a hat-trick in Saturday's 5-1 win at home to Sevilla, the latest milestone for the four-times World Player of the Year.
Images from the football matches played on Tuesday.
Luka Modric has signed a one-year contract extension with Real Madrid
Lionel Messi wasted little time in finding his stride as he struck twice to lead 10-man Barcelona to a 3-0 home win over Elche and hand new coach Luis Enrique a happy start to the La Liga season on Sunday.
Champions Real Madrid earned a 2-0 win in a feisty LaLiga encounter at Athletic Bilbao on Sunday to ensure they stayed in the hunt for the LaLiga title with leaders Barcelona.
Champions Barcelona suffered a humiliating 2-0 home defeat to Hercules on Saturday when Nelson Valdez struck twice to give the tiny promoted club a shock La Liga victory at a stunned Nou Camp stadium.
IMAGES from the soccer matches played across European leagues over the weekend.
Diego Costa scored twice as Atletico Madrid beat Valencia 3-0 to maintain their winning home run this season and keep pace with Barcelona at the top of the La Liga table.
Barcelona's bid for a fourth straight La Liga title is foundering due to their erratic away form but Tuesday's 3-1 Champions League victory at Bayer Leverkusen suggests they are unlikely to suffer the same problem in Europe.
Real Madrid conceded a late freekick to draw for the second time in four days as they were held 1-1 at struggling Villarreal, cutting their lead at the top of La Liga cut to six points on Wednesday.
Casemiro headed an 89th minute winner to earn Real Madrid a barely deserved 2-1 victory at Las Palmas in La Liga on Sunday as they closed the gap on second-placed Atletico Madrid to four points.
Cristiano Ronaldo kept up his rich La Liga scoring form as Real Madrid beat Villarreal 2-0 on Saturday to move up to fourth.
Seven times reigning winner Lionel Messi was not nominated for this year's Ballon d'Or for the first time since 2005 and nor was his Paris Saint-Germain team mate Neymar.
Barcelona stayed hard on the heels of La Liga leaders Real Madrid when Lionel Messi's brilliance lifted a side containing several youngsters from the club's B team to a 2-1 win at home to Real Sociedad on Saturday.
Barcelona slipped five points behind La Liga leaders Real Madrid when Alvaro Vazquez netted a shock late equaliser to snatch a 1-1 draw for Espanyol in the Catalan derby on Sunday.
Real Madrid climbed back above Barcelona to the top of La Liga when goals from former Liverpool pair Xabi Alonso and Alvaro Arbeloa helped them to a stirring 3-2 comeback win over Atletico Madrid on Sunday.
Rafael van der Vaart admitted to handling the ball in the lead up to Real Madrid's opening goal in their 3-1 victory over Sporting Gijon in La Liga on Saturday.
Barcelona failed to capitalise on Real Madrid dropping points against Villarreal as the La Liga champions were held to a 1-1 draw at home to Atletico Madrid on Wednesday, while talisman Lionel Messi limped off with a groin injury.
Barca said the move was part of their efforts to bring soccer and music together.
Sevilla's devastating display to dispatch Malaga 4-1 on Saturday put them in their highest league position after 16 games for a decade and left little doubt that hiring coach Jorge Sampaoli to succeed serial winner Unai Emery was the right choice.
A late double from Cristiano Ronaldo put some gloss on a stuttering performance from Real Madrid as they beat Celta Vigo 3-0 to cut the gap at the top of La Liga to five points.
Atletico Madrid made a typically aggressive start to lay the foundations for a 2-0 victory at home.
Barcelona's 2-1 loss at Ajax Amsterdam in the Champions League last week was down to a lack of intensity while Sunday's 1-0 reverse at Athletic Bilbao in La Liga exposed their relative physical frailty.
Images from the La Liga matches played across Spain on Saturday.